N-[2-bromo-5-[(E)-hydroxyiminomethyl]pyridin-3-yl]-2,2-dimethylpropanamide
N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide
CAS: 1142192-46-8
Molecular Formula: C11H14BrN3O2
N-[2-bromo-5-[(E)-hydroxyiminomethyl]pyridin-3-yl]-2,2-dimethylpropanamide - Names and Identifiers
N-[2-bromo-5-[(E)-hydroxyiminomethyl]pyridin-3-yl]-2,2-dimethylpropanamide - Physico-chemical Properties
| Molecular Formula | C11H14BrN3O2 |
| Molar Mass | 300.15 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12026765 |
N-[2-bromo-5-[(E)-hydroxyiminomethyl]pyridin-3-yl]-2,2-dimethylpropanamide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
N-[2-bromo-5-[(E)-hydroxyiminomethyl]pyridin-3-yl]-2,2-dimethylpropanamide - Introduction
N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide is an organic compound whose chemical formula is C12H15BrN3O2. The properties and uses of the compound are as follows:
Nature:
-Appearance: White to yellow solid
-Molecular weight: 325.17g/mol
-Melting point: 124-127 degrees Celsius
-Solubility: Soluble in some organic solvents, such as chloroform and dichloromethane
-Water Soluble: Insoluble in water
Use:
N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide are mainly used in the field of organic synthesis. It can be used as an intermediate or catalyst for the synthesis of other compounds, such as drugs, pesticides, dyes and photosensitizers.
Preparation Method:
The preparation of N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide generally involves the following steps:
1. First, 2-amino-5-bromomethylpyridine reacts with hydroxime hydrochloride to generate N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)hydroxylamine.
2. Then, the N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)hydroxylamine is reacted with a basic quaternary ammonium nitrile to produce N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide.
Safety Information:
There is limited safety information about this compound, so it is necessary to take protective measures when handling it and follow the laboratory's safe operating procedures. In addition, the compound may be potentially harmful to the environment, so handling and disposal should comply with relevant environmental protection regulations. When using or handling the compound, care should be taken to avoid contact with skin, eyes and inhalation of its dust. If exposed or inhaled, rinse immediately with water and seek medical help.
Nature:
-Appearance: White to yellow solid
-Molecular weight: 325.17g/mol
-Melting point: 124-127 degrees Celsius
-Solubility: Soluble in some organic solvents, such as chloroform and dichloromethane
-Water Soluble: Insoluble in water
Use:
N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide are mainly used in the field of organic synthesis. It can be used as an intermediate or catalyst for the synthesis of other compounds, such as drugs, pesticides, dyes and photosensitizers.
Preparation Method:
The preparation of N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide generally involves the following steps:
1. First, 2-amino-5-bromomethylpyridine reacts with hydroxime hydrochloride to generate N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)hydroxylamine.
2. Then, the N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)hydroxylamine is reacted with a basic quaternary ammonium nitrile to produce N-(2-Bromo-5-((hydroxyimino)methyl)pyridin-3-yl)-pivalamide.
Safety Information:
There is limited safety information about this compound, so it is necessary to take protective measures when handling it and follow the laboratory's safe operating procedures. In addition, the compound may be potentially harmful to the environment, so handling and disposal should comply with relevant environmental protection regulations. When using or handling the compound, care should be taken to avoid contact with skin, eyes and inhalation of its dust. If exposed or inhaled, rinse immediately with water and seek medical help.
Last Update：2024-04-09 21:54:55
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